Analysis of total and specific IgE in serum of carvota mitis pollen-induced allergic rhinitis patients / 临床耳鼻咽喉头颈外科杂志

ABSTRACT

OBJECTIVE@#Exploring the relationship between total and specific IgE in serum and allergen skin test of carvota mitis pollen-induced allergic rhinitis patients.@*METHOD@#Four hundred and-twenty-nine carvota mitis pollen-induced allergic rhinitis patients and 243 healthy control subjects were recruited. The experimental group carried out skin tests. and pollen-specific IgE were also examined by BSA-ELISA method. Total IgE in serum of all of the subjects were determined by ELISA.@*RESULT@#The positive rate of the total IgE level of the patients were much higher than those of the controls (66.2% vs. 15.6%, P 0.05). The difference between serum-specific IgE and total IgE was statistically significant (chi2 = 50.639, P 0.05).@*CONCLUSION@#Allergen skin test and carvota mitis pollen-specific IgE are two effective methods for the diagnosis of carvota mitis pollen-induced allergic rhinitis. The detection of total IgE in serum of carvota mitis pollen-induced allergic rhinitis provides a reference value for diagnosis. The relationship between concentration of IgE in serum of the carvota mitis pollen-induced allergic rhinitis and allergen contact duration is waiting for further study.