The efficacy of single premedication with antihistamines for radiocontrast media hypersensitivity
Asia Pacific Allergy
;
(4): 164-167, 2016.
Article
Dans Anglais
| WPRIM
| ID: wpr-750070
ABSTRACT
BACKGROUND:
Single premedication with antihistamines for radiocontrast media (RCM) hypersensitivity is frequently used in real world at the emergent situation although its efficacy is not proven.OBJECTIVE:
To evaluate the effect of intravenous antihistamines as a premedication in general population who had experience of mild adverse reactions to iodinated RCM.METHODS:
A retrospective observational study on 14,785 subjects who had RCM-enhanced computed tomography scans between January 2014 and December 2015 in Seoul National University Hospital Gangnam Healthcare Center, Seoul, South Korea.RESULTS:
Among 453 subjects who had a history of mild RCM-induced hypersensitivity reactions, 273 subjects had a single premedication of intravenous antihistamine. When comparing antihistamine-premedication group and nonpremedication group, there is no protective effect of antihistamines on the incidence rate and severity of hypersensitivity (10.6% vs. 11.7%, p = 0.729).CONCLUSION:
The clinical efficacy of a single premedication of antihistamines for mild RCM-induced hypersensitivity was not confirmed.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Prémédication
/
Incidence
/
Études rétrospectives
/
Résultat thérapeutique
/
Produits de contraste
/
Prestations des soins de santé
/
Étude d'observation
/
Séoul
/
Antihistaminiques
/
Hypersensibilité
Type d'étude:
Etude d'incidence
/
Étude observationnelle
/
Étude pronostique
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Asia Pacific Allergy
Année:
2016
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS