Research progress on the relationship between autism and intestinal microbiota / 国际儿科学杂志

ABSTRACT

There are trillions of microbes in human gut, which are related to health and diseases close-ly. In recent years, with the popularization of the concept of microbiome-gut-brain axis, the influence of intesti-nal microbiota on central nervous system diseases has drawn increasing attention. Gastrointestinal symptoms are common in children with autism spectrum disorder ( ASD) , and some studies have also indicated that correc-ting the dysbiosis of gut microbiome can not only improve the gastrointestinal problems, but also alleviate the symptoms of autism to some extent. Therefore, the relationship between intestinal microbes and ASD has attrac-ted researchers' attention. This review focuses on several kinds of gut microbesmicrotes that have been exten-sively studied to reveal the relationship between the microbesmicrotes and autism spectrum disorders and their potential pathogenic or protective mechanisms.