Quantitativeassessmentofinvasivepulmonaryadenocarcinoma aspuregroundglassnoduleusingthin-sliceCT / 实用放射学杂志

ABSTRACT

Objective ToexploretheCTcharacteristicsofinvasivepulmonaryadenocarcinomapresentingaspuregroundglass nodule(pGGN)withthin-sliceCT,andtodifferentiateinfiltratingadenocarcinoma(IA)fromnon-IA.Methods 271patientswith pGGNconfirmedbysurgicalpathologywereenrolledinthisstudyforretrospectiveanalysis.Patientsweredividedinto4groups:18 atypicaladenomatoushyperplasias(AAH),114adenocarcinomasinsitu(AIS),82minimallyinvasiveadenocarcinomas(MIA)and 57IA.Allthepatientsunderwentthin-sliceCTscansin1weekbeforesurgery.ThemaximumdiameterandaverageCTvaluewere measured,andtheimagingcharacteristicsofallpGGN,includingpleuralinelentationandvacuolesignwererecorded.Results The maximumdiameter,averageCTvalue,age,vacuolesignandsmokinghistory weresignificantlydifferent (P<0.05)betweenIA groupandnon-IAgroup.Nosignificantstatisticaldifferenceswereobservedingenderandpleuralindentation.Thediagnosticefficacy ofthemaximumdiameterandaverageCTvalueweregoodandtheROCcurveswere0.876and0.802respectively.Conclusion Itis helpfultodifferentiateIAgroupfromnon-IAgroupusingthemaximumdiameter,theaverageCTvalue,age,vacuolesignandsmoking history.ThemaximumdiameterandaverageCTvalueofIAgrouparesignificantlyhigherthannon-IAgroup.