Clinical characteristics of 27 patients with type 1 autoimmune pancreatitis / 中华肝胆外科杂志
Chinese Journal of Hepatobiliary Surgery
;
(12): 592-595, 2019.
Article
Dans Chinois
| WPRIM
| ID: wpr-755175
ABSTRACT
Objective To analyze the clinical characteristics of type 1 autoimmune pancreatitis (AIP) in patients.Methods The clinical data of 27 patients with type 1 AIP treated at Fujian Provincial Hospital from January 2012 to October 2018 were retrospectively analyzed.Results There are 25 males (92.6%) and 2 females (7.4%) (ratio 12.5∶1).The age of disease onset was (59.5 ± 14.3) years.The most common presenting symptoms were jaundice and abdominal pain (both 59.3%).The most common complication was IgG4-related sclerosing cholangitis (63.0%).Magnetic Resonance Cholangiopancreatograhpy (MRCP) conducted on 26 patients showed the diffuse type 1 AIP was most common (53.8%),only 2 patients (7.7%) presented with a main pancreatic duct stricture.The pancreatic segment of bile duct narrowing was very common (84.6%),and most patients presented as tapered narrowings (65.4%).Standard glucocorticoid therapy was given to these 27 patients who responded well with clinical and laboratory remissions.Two patients were given maintenance glucocorticoid therapy for a high level of serum IgG4.Conclusions Type 1 AIP can present as a local manifestation of IgG4-related disease.The most common complication is IgG4-related sclerosing cholangitis.Glucocorticoid therapy was effective but some patients required maintenance therapy.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Chinese Journal of Hepatobiliary Surgery
Année:
2019
Type:
Article
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