A versatile building block: the structures and functions of negative-sense single-stranded RNA virus nucleocapsid proteins
Protein & Cell
;
(12): 893-902, 2012.
Article
Dans Anglais
| WPRIM
| ID: wpr-757847
ABSTRACT
Nucleocapsid protein (NPs) of negative-sense single-stranded RNA (-ssRNA) viruses function in different stages of viral replication, transcription, and maturation. Structural investigations show that -ssRNA viruses that encode NPs preliminarily serve as structural building blocks that encapsidate and protect the viral genomic RNA and mediate the interaction between genomic RNA and RNA-dependent RNA polymerase. However, recent structural results have revealed other biological functions of -ssRNA viruses that extend our understanding of the versatile roles of virally encoded NPs.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Physiologie
/
Virus à ARN
/
Chimie
/
Capside
/
Orthobunyavirus
/
Protéines nucléocapside
/
Virus de Lassa
/
Métabolisme
Limites du sujet:
Animaux
/
Humains
langue:
Anglais
Texte intégral:
Protein & Cell
Année:
2012
Type:
Article
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