Clinical Outcomes of Ileostomy Closure According to Timing During Adjuvant Chemotherapy After Rectal Cancer Surgery
Annals of Coloproctology
;
: 187-193, 2019.
Article
Dans Anglais
| WPRIM
| ID: wpr-762318
ABSTRACT
PURPOSE:
No guidelines exist detailing when to implement a temporary ileostomy closure in the setting of adjuvant chemotherapy following sphincter-saving surgery for rectal cancer. The aim of this study was to evaluate the clinical and oncological outcomes of ileostomy closure during adjuvant chemotherapy in patients with curative resection of rectal cancer.METHODS:
This retrospective study investigated 220 patients with rectal cancer undergoing sphincter-saving surgery with protective loop ileostomy from January 2007 to August 2016. Patients were divided into 2 groups group 1 (n = 161) who underwent stoma closure during adjuvant chemotherapy and group 2 (n = 59) who underwent stoma closure after adjuvant chemotherapy.RESULTS:
No significant differences were observed in operative time, blood loss, postoperative hospital stay, or postoperative complications in ileostomy closure between the 2 groups. No difference in overall survival (P = 0.959) or disease-free survival (P = 0.114) was observed between the 2 groups.CONCLUSION:
Ileostomy closure during adjuvant chemotherapy was clinically safe, and interruption of chemotherapy due to ileostomy closure did not change oncologic outcomes.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Complications postopératoires
/
Tumeurs du rectum
/
Iléostomie
/
Études rétrospectives
/
Traitement médicamenteux adjuvant
/
Survie sans rechute
/
Hémorragie postopératoire
/
Traitement médicamenteux
/
Durée opératoire
/
Durée du séjour
Type d'étude:
Guide de pratique
/
Étude observationnelle
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Annals of Coloproctology
Année:
2019
Type:
Article
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