Association between shift work and hyperhomocysteinemia in male workers
Annals of Occupational and Environmental Medicine
;
: e1-2019.
Article
Dans Anglais
| WPRIM
| ID: wpr-762585
ABSTRACT
BACKGROUND:
Shift work is associated with a higher risk of cardiovascular diseases. Here, we sought to assess the relationship between shift work and plasma homocysteine levels. Determining the correlations between shift work and homocysteine levels may provide a better understanding of the mechanisms underlying cardiovascular diseases.METHODS:
This study was performed using data from routine health examinations of steel workers in 2017. In total, 431 male workers (70 daytime workers and 361 shift workers) employed on a rolling departure schedule were recruited. Plasma homocysteine levels > 15 μmol/L were considered elevated. The χ2, analysis of variance, and multiple logistic regression analyses were used to examine the association between shift work and plasma homocysteine levels.RESULTS:
In comparison to daytime workers, the odds ratio (OR) of hyperhomocysteinemia in individuals with < 10 years of shift work was 1.14 (95% confidence interval [CI] 0.64–2.03), compared to 2.01 (95% CI 1.14–3.54) for workers with ≥ 10 years of experience. After adjusting for confounding variables, the adjusted OR for shift workers with < 10 years of experience was 0.95 (95% CI 0.50–1.80), compared to 2.00 (95% CI 1.07–3.74) for workers with ≥ 10 years of experience.CONCLUSIONS:
The risk of hyperhomocysteinemia was significantly higher in shift workers compared to those working normal daytime hours, particularly among long-term shift workers.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Rendez-vous et plannings
/
Plasma sanguin
/
Acier
/
Maladies cardiovasculaires
/
Modèles logistiques
/
Odds ratio
/
Hyperhomocystéinémie
/
Homocystéine
Type d'étude:
Etude d'étiologie
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Annals of Occupational and Environmental Medicine
Année:
2019
Type:
Article
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