Late complications and current status of long-term survivals over 10 years after Kasai portoenterostomy / 대한외과학회지
Journal of the Korean Surgical Society
;
: 271-275, 2011.
Article
Dans Anglais
| WPRIM
| ID: wpr-76446
ABSTRACT
PURPOSE:
Whereas the Kasai portoenterostomy (KPE) is an accepted first line of surgery for bile drainage in infants with biliary atresia, its long-term effectiveness is not clear because its etiology and pathogenesis remains unknown. This study was aimed to investigate the late complications occurring in long-term survivors and the current status of living patients who survived over 10 years after KPE.METHODS:
A retrospective analysis of the medical records of 32 patients who underwent KPE from 1990 to 2000 was done. We analyzed 10-year survival rates with the Kaplan-Meier method and the current status of the long-term survivors.RESULTS:
The overall 10-year survival rate by Kaplan-Meier method after KPE was 76.2%. Eight (25%) patients had died, including 4 who were transplanted. Nineteen (59.4%) patients survived over 10 years. Among them, 6 (31.6%) patients had portal hypertension, and 5 (26.3%) had episodes of cholangitis. Two had intrahepatic cyst and 2 had intestinal obstruction. Six (31.6%) patients have been well without any complications.CONCLUSION:
The long-term survival rate of biliary atresia is slightly improving. However, two thirds of patients suffer from various complications. One-third of survivors go on without any complication. As biliary atresia is known as a progressive inflammatory disease, careful life-long follow- up is needed in long-term survivals after KPE.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Bile
/
Atrésie des voies biliaires
/
Hépato-porto-entérostomie
/
Drainage
/
Angiocholite
/
Dossiers médicaux
/
Taux de survie
/
Études rétrospectives
/
Survivants
/
Transplants
Type d'étude:
Étude observationnelle
Limites du sujet:
Humains
/
Bébé
langue:
Anglais
Texte intégral:
Journal of the Korean Surgical Society
Année:
2011
Type:
Article
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