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Evaluation of RF300 for Leukoreduction of Red Blood Cells / 대한수혈학회지
Korean Journal of Blood Transfusion ; : 13-19, 2012.
Article Dans Anglais | WPRIM | ID: wpr-76698
ABSTRACT

BACKGROUND:

Use of universal leukoreduction for prevention of leukocyte associated transfusion reactions is common practice in many countries. This study was conducted in order to evaluate the performance of a newly developed leukoreduction filter for red blood cells (RBCs), the RF300 (Kolon Industries, Inc, Gumi, Korea).

METHODS:

Filtration time, RBC recovery, residual leukocyte count, and leukocyte removal rate were evaluated. To assess the quality of RBCs after filtration, percent hemolysis was monitored for a period of 21 days. Performance of the RF300 (N=78) was compared with that of the Bio-R O2 plus (Fresenius, Hamburg, Germany), the Pall Purecell RC (Pall Co., Washington, USA), and the Sepacell R-500N (Asahi, Tokyo, Japan).

RESULTS:

The shortest filtration time was observed using the RF300 (P<0.05). Using the RF300, recovery of RBC was 96.5%, which was higher than that of two filters (P<0.05). Mean residual leukocyte count was 0.26x10(6)/unit, with a leukocyte removal rate of 3 log. Using the RF300, mean percent hemolysis was 0.32% at day 21, which was comparable with that of two filters, but lower than that of one filter (P<0.05).

CONCLUSION:

The RF300 meets all established quality requirements for conduct of safe and effective leukoreduction of RBCs.
Sujets)

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Tokyo / Incompatibilité sanguine / Washington / Collodion / Érythrocytes / Filtration / Hémolyse / Numération des leucocytes / Leucocytes Pays comme sujet: Amérique du Nord / Asie langue: Anglais Texte intégral: Korean Journal of Blood Transfusion Année: 2012 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Tokyo / Incompatibilité sanguine / Washington / Collodion / Érythrocytes / Filtration / Hémolyse / Numération des leucocytes / Leucocytes Pays comme sujet: Amérique du Nord / Asie langue: Anglais Texte intégral: Korean Journal of Blood Transfusion Année: 2012 Type: Article