Qualitative characterization of flavonoids in Scutellariae Radix by using PREC-IDA-EPI / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 345-352, 2018.
Article
Dans Chinois
| WPRIM
| ID: wpr-771731
ABSTRACT
Flavonoids are the most abundant constituents and induce these the rapeutic effects against inflammation, gastrointestinal infections, cardiovascular diseases, and respiratory. Most of these flavonoids have low content in Scutellarie Radix. It was difficult to detect some minor compounds by using LC-MS method with full scan. Based on the review of flavonoids that had been extracted from Scutellariae Radix, a method with PREC-IDA-EPI technique was developed and applied to Scutellariae Radix by using UPLC-MS/MS. A total of 97 flavonoids were identified, including 29 aglycones and 68 -glycosides. This study laid the foundation for pharmacodynamicss of Scutellariae Radix.It is believed that an individual detection scheme based on the PREC-IDA-EPI technique could be used to identify unknown compounds.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Flavonoïdes
/
Médicaments issus de plantes chinoises
/
Chimie
/
Chromatographie en phase liquide
/
Scutellaria baicalensis
/
Spectrométrie de masse en tandem
Type d'étude:
Recherche qualitative
langue:
Chinois
Texte intégral:
China Journal of Chinese Materia Medica
Année:
2018
Type:
Article
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