Carbazole alkaloids isolated from the branch and leaf extracts of Clausena lansium / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 509-512, 2018.
Article
Dans Anglais
| WPRIM
| ID: wpr-773589
ABSTRACT
The present study carried out a phytochemical investigation of the methanol extract of the branches and leaves of Clausena lansium and afforded nine carbazole alkaloids (compounds 1-9) including two new carbazole alkaloids, claulansiums A and B (compounds 1 and 2). The new compounds were elucidated on the basis of extensive spectroscopic data (MS, NMR, IR, and UV) and the known compounds were identified by comparing spectroscopic data with those reported in literature. All the isolated compounds were tested for their cytotoxic activity against A549 and Hela cancer cell lines. Our results showed that compounds 2-6 exhibited varying degrees of cytotoxicity to cancer cells, with IC values ranging from 8.67 to 98.89 μmol·L.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Plantes médicinales
/
Carbazoles
/
Extraits de plantes
/
Cellules HeLa
/
Structure moléculaire
/
Survie cellulaire
/
Chimie
/
Tiges de plante
/
Feuilles de plante
/
Lignée cellulaire tumorale
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Chinese Journal of Natural Medicines (English Ed.)
Année:
2018
Type:
Article
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