Survival Analysis of 148 Patients with Primary Diffuse Large B Cell Lymphoma / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 61-66, 2019.
Article
Dans Chinois
| WPRIM
| ID: wpr-774358
ABSTRACT
OBJECTIVE@#To investigate the clinical outcome of the patients with primary diffuse large B-cell lymphoma(DLBCL).@*METHODS@#Clinical data of 148 patients with DLBCL in our hospital and cancer hospital from March 2006 to April 2016 were retrospectively analyzed. Kaplan-Meier analysis was used to estimate progression-free survival(PFS)and overall survival(OS).@*RESULTS@#5-year OS and PFS rates were 85% and 69%,respectively. The survival analysis showed that 5-year OS rate of R-CHOP group was significantly higher than that of CHOP alone group(89% vs. 70%,P60 years),poor ECOG score(≥2),advanced stage(Ⅲ-Ⅳ),higher IPI score(≥3),CHOP alone and absence of radiotherapy related with poor survival rate. Furthermore,multivariate analysis showed that age>60 year significantly related with the worse OS.@*CONCLUSION@#Age >60 year is an important independent prognostic factor to predict worse OS or PFS.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pronostic
/
Protocoles de polychimiothérapie antinéoplasique
/
Doxorubicine
/
Études rétrospectives
/
Lymphome B diffus à grandes cellules
/
Survie sans rechute
/
Cyclophosphamide
/
Anticorps monoclonaux d'origine murine
Type d'étude:
Étude observationnelle
/
Étude pronostique
Limites du sujet:
Humains
langue:
Chinois
Texte intégral:
Journal of Experimental Hematology
Année:
2019
Type:
Article
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