Quantitative analysis and stability of -hydroxybenzyl hydrogen sulfite in sulfur-fumigated Gastrodiae Rhizoma / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 248-253, 2018.
Article
Dans Zh
| WPRIM
| ID: wpr-776395
Responsable en Bibliothèque :
WPRO
ABSTRACT
Studies on the characteristic chemical markers of sulfur fumigation have become an effective auxiliary way for quality control of traditional Chinese medicine. This study established a quantitative analysis method for the determination of -hydroxybenzyl hydrogen sulfite (-HS) in Gastrodiae Rhizoma (GR) based on UPLC-MS/MS. Then, 37 batches of GR were screened, and the results showed that 27 batches of them were sulfur-fumigated. Especially, the GR samples in Yunnan producing areas were sulfur-fumigated more seriously. Based on the stability of -HS after different storage time and heat treatment methods, it was found that the content of -HS was stable and reliable in the storage period of 8 months and under normal heat treatment (50, 60, 70, 80 °C) conditions. In conclusion, this study shows a high sensitivity, good selectivity and good stability of -HS, which can provide reference for the quality control and sulfur fumigation screening of GR.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Contrôle de qualité
/
Normes de référence
/
Sulfites
/
Soufre
/
Médicaments issus de plantes chinoises
/
Chimie
/
Chine
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Fumigation
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Chromatographie en phase liquide
/
Rhizome
Pays comme sujet:
Asia
langue:
Zh
Texte intégral:
China Journal of Chinese Materia Medica
Année:
2018
Type:
Article