Clinical effect of combined treatment with Kangfuxin solution and dexamethasone on erosive oral lichen planus / 口腔疾病防治

ABSTRACT

Objective @# To observe the clinical effect of combined treatment with Kangfuxin solution and dexamethasone on erosive oral lichen planus (OLPe). @*Methods @# One hundred OLPe patients were randomly divided into two groups (n=50). The experimental group was treated with 9.8% Kangfuxin solution along with dexamethasone solution three times a day. The control group was treated with dexamethasone solution three times a day. Before treatment and 1, 2 and 4 weeks after treatment, the Visual Analogue Scale (VAS) score and erosion area were measured, and the total effective rate was compared between the two groups. @*Results @#After 1, 2, and 4 weeks of treatment, the VAS score and erosion area were lower in the experimental group than in the control group (P < 0.05). After 4 weeks of treatment, the total effective rate in the experimental group was 92%, significantly higher than that in the control group (P < 0.05). @*Conclusion @#Compared with dexamethasone alone, Kangfuxin solution combined with dexamethasone is more effective for the treatment of OLPe.