Research advances in prognostic factors for patients with esophagogastric variceal bleeding / 临床肝胆病杂志

ABSTRACT

Esophagogastric variceal bleeding is one of the most common complications of liver cirrhosis and is also one of the most critical diseases in the department of gastroenterology, with the features of acute onset and high rebleeding and mortality rates. Strengthening the understanding of related prognostic factors has great clinical significance in reducing early rebleeding rate and mortality rate. There are many factors associated with rebleeding and death in patients with esophagogastric variceal bleeding. Risk factors include advanced age, sex, Child-Turcotte-Pugh class C, low platelet count, high leukocyte count, bleeding history, portal broadening, widening of the portal vein, a positive red-color sign under an endoscope, severe varices, and infection, while the percentage of lymphocytes, serum sodium, and the use of non-selective β-blockers and antibiotics are protective factors. By analyzing these prognostic factors, we can learn more about their mechanisms and risk degree. At present, related research mainly focuses on the exploration of better individual treatment regimens and nursing strategies based on the risk assessment models established using these risk factors to reduce the risk of rebleeding and death.