Research progress of indoleamine 2,3-dioxygenase 1 in tumor immunotherapy / 药学学报
Acta Pharmaceutica Sinica
;
(12): 1271-1278, 2018.
Article
Dans Chinois
| WPRIM
| ID: wpr-779997
ABSTRACT
IDO1 (indoleamine 2,3-dioxygenase 1) is one of the most significant checkpoint in tumor immunology. Numerous studies indicates that IDO1 is abnormally expressed in breast cancer, colorectal cancer, liver cancer and other tumor tissues, participating in tumor immune escape through multiple pathways. This review is prepared to elucidate the biological function of IDO1, highlight its pivotal role in tumor evasion, and summarize IDO1 inhibitors in the clinical trials.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Acta Pharmaceutica Sinica
Année:
2018
Type:
Article
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