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Selection criteria and colpotomic approach for safe minimally invasive radical hysterectomy in early-stage cervical cancer / 부인종양
Journal of Gynecologic Oncology ; : 7-2020.
Article Dans Anglais | WPRIM | ID: wpr-782095
ABSTRACT
OBJECTIVE: To evaluate oncologic outcomes of minimally invasive radical hysterectomy (RH) in early cervical cancer before and after the application of parametrial invasion (PMI) criterion on magnetic resonance imaging (MRI) and vaginal colpotomy (VC).

METHODS:

A total of 216 International Federation of Gynecology and Obstetrics stage IB–IIA cervical cancer patients who underwent minimally invasive RH was identified between April 2006 and October 2018. Patients were classified into the pre-PMI intracorporeal or VC (IVC) (n=117) and post-PMI VC groups (n=99). In the pre-PMI IVC group, PMI criterion (intact stromal ring) on MRI was not applied and the patients received IVC. In the post-PMI VC group, surgical candidates were selected using the PMI criterion on MRI and all patients received VC only. Oncologic outcomes and prognostic factors associated with disease recurrence were analyzed.

RESULTS:

The rate of positive vaginal cuff margins in the pre-PMI IVC group was higher than that in the post-PMI VC group (11.1% vs. 1.0%, p=0.003). Two-year disease-free survival was different between the 2 groups (84.5% in pre-PMI IVC vs. 98.0% in post-PMI VC groups, p=0.005). Disrupted stromal ring on MRI (hazard ratio [HR]=20.321; 95% confidence interval [CI]=4.903–84.218; p<0.001) and intracorporeal colpotomy (HR=3.059; 95% CI=1.176–7.958; p=0.022) were associated with recurrence.

CONCLUSION:

The intact cervical stromal ring on MRI might identify the low-risk group of patients in terms of PMI and lymphovascular/stromal invasion in early cervical cancer. Minimally invasive RH should be performed in optimal candidates with an intact stromal ring on MRI, using VC.
Sujets)

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Récidive / Imagerie par résonance magnétique / Tumeurs du col de l&apos;utérus / Sélection de patients / Survie sans rechute / Interventions chirurgicales mini-invasives / Colpotomie / Gynécologie / Hystérectomie / Obstétrique Type d'étude: Étude pronostique Limites du sujet: Humains langue: Anglais Texte intégral: Journal of Gynecologic Oncology Année: 2020 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Récidive / Imagerie par résonance magnétique / Tumeurs du col de l&apos;utérus / Sélection de patients / Survie sans rechute / Interventions chirurgicales mini-invasives / Colpotomie / Gynécologie / Hystérectomie / Obstétrique Type d'étude: Étude pronostique Limites du sujet: Humains langue: Anglais Texte intégral: Journal of Gynecologic Oncology Année: 2020 Type: Article