Autoimmune Hepatic Failure Following Acute Hepatitis A is Accompanied by Inflammatory Conversion of Regulatory T Cells
Yonsei Medical Journal
;
: 100-102, 2020.
Article
Dans Anglais
| WPRIM
| ID: wpr-782117
ABSTRACT
autoimmune hepatitis (AIH) following acute hepatitis A (AHA) in immunologic aspects, we performed multi-color flow cytometry with peripheral blood mononuclear cells of a patient who underwent liver transplantation due to AIH-induced liver failure. Unlike general AHA patients, the proportion of tumor necrosis factor-α-producing Treg cells remained high for 6 months after diagnosis of AHA until she underwent a liver transplantation. The conversion of Treg cells into mediators of inflammation may have played a role in the autoimmune pathogenesis following AHA.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Transplantation hépatique
/
Défaillance hépatique
/
Lymphocytes T régulateurs
/
Médiateurs de l'inflammation
/
Hépatite auto-immune
/
Diagnostic
/
Cytométrie en flux
/
Hépatite
/
Hépatite A
/
Nécrose
Type d'étude:
Etude diagnostique
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Yonsei Medical Journal
Année:
2020
Type:
Article
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