Pathology of C3 Glomerulopathy
Childhood Kidney Diseases
;
: 93-99, 2019.
Article
Dans Anglais
| WPRIM
| ID: wpr-785578
ABSTRACT
C3 glomerulopathy is a renal disorder involving dysregulation of alternative pathway complement activation. In most instances, a membranoproliferative pattern of glomerular injury with a prevalence of C3 deposition is observed by immunofluorescence microscopy. Dense deposit disease (DDD) and C3 glomerulonephritis (C3GN) are subclasses of C3 glomerulopathy that are distinguishable by electron microscopy. Highly electron-dense transformation of glomerular basement membrane is characteristic of DDD. C3GN should be differentiated from post-infectious glomerulonephritis and other immune complex-mediated glomerulonephritides showing C3 deposits.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Anatomopathologie
/
Microscopie électronique
/
Glomérulonéphrite membranoproliférative
/
Prévalence
/
Activation du complément
/
Voie alterne d'activation du complément
/
1,1-Dichloro-2,2-bis(4-chlorophényl)éthane
/
Membrane basale glomérulaire
/
Glomérulonéphrite
/
Microscopie de fluorescence
Type d'étude:
Étude de prévalence
langue:
Anglais
Texte intégral:
Childhood Kidney Diseases
Année:
2019
Type:
Article
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