Ocular Manifestations of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis / 한양의대학술지
Hanyang Medical Reviews
;
: 174-181, 2016.
Article
Dans Anglais
| WPRIM
| ID: wpr-78645
ABSTRACT
Steven-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare and sometimes life-threatening hypersensitivity mucocutaneous disease triggered mostly by medication and infections Major involving tissues are the mucous membranes of oral, gastrointestinal, respiratory, integument, and gynecologic tissues. Even after recovering from skin problems without sequelae, survivors can have serious ocular complications leading to blindness despite local and systemic therapy. There is no definite effective systemic and local treatment for SJS/TEN. Early detection and aggressive treatment are important for the long-term prognosis of the eye. Eyelid margin and palpebral conjunctiva and fornix should be checked thoroughly to detect the cicatrical changes that make chronic ocular surface failure such as limbal cell deficiency and complete ocular surface keratinization. Amniotic membrane transplantation and cultivated oral mucosal graft are beneficial to reduce the risk of ocular surface failure.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pronostic
/
Peau
/
Cécité
/
Syndrome de Stevens-Johnson
/
Survivants
/
Conjonctive
/
Transplants
/
Paupières
/
Amnios
/
Hypersensibilité
Type d'étude:
Étude pronostique
/
Étude de dépistage
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Hanyang Medical Reviews
Année:
2016
Type:
Article
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