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Clinical Significance of Incidental Focal ¹⁸F-FDG Uptake in the Spinal Cord of Patients with Cancer / 대한핵의학회잡지
Korean Journal of Nuclear Medicine ; : 247-251, 2017.
Article Dans Anglais | WPRIM | ID: wpr-786934
ABSTRACT

PURPOSE:

We investigated the incidence, location, and clinical significance of focal ¹⁸F-FDG uptake of the spinal cord in patients with cancer.

METHODS:

We reviewed the medical records of 22,937 consecutive adult patients with known or suspicious malignancy who underwent ¹⁸F-FDG PET/CT. PET/CT scans with incidental focal spinal cord uptake were selected and retrospectively reviewed to determine the presence, location, number, and maximum standardized uptake value (SUV(max)) of any focal hypermetabolic lesions of the spinal cord. In subjects with focal spinal uptake, clinical characteristics and clinical follow-up results, including follow-up PET/CT, were reviewed.

RESULTS:

Incidental focal spinal cord uptake was observed in 69 of 22,937 adult patients (incidence = 0.3%; MF = 3138; age, 55.8 ± 14.7 years). Seventy-eight focal hypermetabolic lesions on spinal cord in the PET/CT scans of the 69 study subjects were analyzed. The most common sites of focal spinal cord uptake were the T12 vertebra (47/78; 60.3%) and L1 vertebra (20/78; 25.6%). Multifocal cord uptake was found in 8 of 69 patients (11.6%). The average SUV(max) for cord uptake was 2.5 ± 0.5 (range, 1.4∼3.9). There was no clinical or imaging evidence of abnormalities in the spinal cord, both at the time of PET/CT and during clinical follow-up.

CONCLUSIONS:

Although incidental focal ¹⁸F-FDG uptake of the spinal cord is rare in patients with cancer, it may be physiological or benign, but it should not be considered as malignant involvement. Common sites for the uptake were in the T12 and L1 spine levels.
Sujets)

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Moelle spinale / Rachis / Dossiers médicaux / Incidence / Études rétrospectives / Études de suivi / Diagnostic différentiel / Tomographie par émission de positons couplée à la tomodensitométrie Type d'étude: Etude diagnostique / Etude d'incidence / Étude observationnelle / Étude pronostique / Facteurs de risque Limites du sujet: Adulte / Humains langue: Anglais Texte intégral: Korean Journal of Nuclear Medicine Année: 2017 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Moelle spinale / Rachis / Dossiers médicaux / Incidence / Études rétrospectives / Études de suivi / Diagnostic différentiel / Tomographie par émission de positons couplée à la tomodensitométrie Type d'étude: Etude diagnostique / Etude d'incidence / Étude observationnelle / Étude pronostique / Facteurs de risque Limites du sujet: Adulte / Humains langue: Anglais Texte intégral: Korean Journal of Nuclear Medicine Année: 2017 Type: Article