Deep Vein Thrombosis in Patients with Pulmonary Embolism: Prevalance, Clinical Significance and Outcome
Vascular Specialist International
; : 166-174, 2016.
Article
Dans En
| WPRIM
| ID: wpr-78758
Responsable en Bibliothèque :
WPRO
ABSTRACT
PURPOSE: Deep venous thrombosis (DVT) and pulmonary embolism (PE) are considered as similar disease entities representing different clinical manifestations. The objectives of this study were: 1) to determine the prevalence and outcome of DVT in patients with PE; 2) to identify additional risk factors for PE-related unfavorable outcome and 30-day all-cause mortality; and 3) to establish the clinical importance of screening for concomitant DVT. MATERIALS AND METHODS: From January 2013 to December 2015, a total of 141 patients with confirmed PE were evaluated. The prevalence and outcome of DVT in patients with PE was determined. Furthermore, the potential risk factors for PE-related unfavorable outcome and 30-day all-cause mortality were also analyzed. RESULTS: The prevalence of concomitant DVT was 45.4%. PE-related unfavorable outcome was observed in 21.9% of all concomitant DVT, with all-cause mortality of 21.9%. There was no significant relationship between the presence of concomitant DVT and the development of PE-related unfavorable outcome or all-cause mortality. Our results indicated that heart rate >100/min and peripheral oxygen saturation <90% were independent predictors for PE-related unfavorable outcome. Regarding all-cause mortality, active malignancy and hypotension or shock were significant risk factors. CONCLUSION: Our findings demonstrate that approximately half of patients with PE possess DVT. However, this study failed to establish any clinical significance of concomitant DVT for PE-related unfavorable outcome and all-cause mortality. Tachycardia and hypoxemia were identified as significant predictors for PE-related unfavorable outcome along with active malignancy and hypotension or shock as significant risk factors of all-cause mortality.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Oxygène
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Embolie pulmonaire
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Choc
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Tachycardie
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Dépistage de masse
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Prévalence
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Facteurs de risque
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Mortalité
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Thrombose veineuse
/
Rythme cardiaque
Type d'étude:
Etiology_studies
/
Prevalence_studies
/
Prognostic_studies
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Risk_factors_studies
/
Screening_studies
Limites du sujet:
Humans
langue:
En
Texte intégral:
Vascular Specialist International
Année:
2016
Type:
Article