Roles and mechanisms of chemokine CX3CL1 in cerebral ischemia / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases
;
(12): 706-710, 2019.
Article
Dans Chinois
| WPRIM
| ID: wpr-789100
ABSTRACT
Chemokine CX3CL1 mainly participates in the physiological and pathological processes of nervous system by activating its receptor CX3CR1.Under physiological conditions,CX3CL1 can inhibit the activation of microglia;when cerebral ischemia and hypoxia,CX3CL1 can affect the expression of multiple downstream target genes involved in activation of adenosine receptor,inhibition of Ca 2+ influx,and promotion of blood vessel growth.It is of great significance to improve the energy metabolism disorder and to establish microcirculation around infarcts after cerebral ischemia.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
International Journal of Cerebrovascular Diseases
Année:
2019
Type:
Article
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