Research progress in depression related biomarkers based on omics technology / 药学实践杂志

ABSTRACT

In recent years,the incidences of depression increased year by year due to increased social pressure,which do serious harm to human being both physically and mentally.Studies have shown that the pathogenesis of depression is complicat-ed,mainly related to body′s inflammation,neurotrophic and metabolic processes.There were no sufficient objective bases for the clinical diagnosis of depression.The drug treatment result was not satisfactory.Therefore,biomarkers become more and more important in disease risk prediction,classification,diagnosis and prognosis.The rapid developments in genomics,transcriptom-ics,proteomics,metabolomics and their applications in the diagnosis make it possible to further screen for depression related bio-markers.This article reviewed the research progresses in depression related biomarkers with omics technologies.