Risk factors for the development of Clostridium difficile colitis in a surgical ward / 대한외과학회지
Journal of the Korean Surgical Society
;
: 14-20, 2012.
Article
Dans Anglais
| WPRIM
| ID: wpr-7911
ABSTRACT
PURPOSE:
Clostridium difficile colitis (CDC) is a nosocomial infection. We attempted to discover the risk factors for the development of CDC in patients admitted to our surgical ward.METHODS:
We conducted a retrospective chart review of all patients admitted to our surgical ward between January 2010 and July 2011. CDC was confirmed when toxin A/B or toxin B polymerase chain reaction was detected in the stool and clinical symptoms, such as diarrhea, were present. We divided patients into the CDC and non-CDC groups, and compared the clinical features between the two groups.RESULTS:
The rate of CDC occurrence was 0.4% (19/4,720 patients). Univariate analysis showed that colectomy (P < 0.001), hospital stays longer than 10 days (P < 0.001), aged over 55 years (P < 0.001) and transfer from medical ward (P = 0.009) were significant parameters for CDC. Multivariate analysis showed that colectomy (P < 0.001; odds ratio [OR], 8.405; 95% confidence interval [CI], 2.927 to 24.132) and hospital stays longer than 10 days (P = 0.035; OR, 10.253; 95% CI, 1.176 to 89.392) were high risk factors for CDC occurrence in the surgical ward.CONCLUSION:
The risk factors for CDC in a surgical ward could be colectomy and a long duration of hospitalization. Therefore, clinicians should consider the possibility of CDC when patients undergo colectomy, are admitted for a long time, and have postoperative diarrhea.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Odds ratio
/
Réaction de polymérisation en chaîne
/
Infection croisée
/
Analyse multifactorielle
/
Études rétrospectives
/
Facteurs de risque
/
Clostridioides difficile
/
Clostridium
/
Colectomie
/
Colite
Type d'étude:
Etude d'étiologie
/
Étude observationnelle
/
Facteurs de risque
Limites du sujet:
Adulte très âgé
/
Humains
langue:
Anglais
Texte intégral:
Journal of the Korean Surgical Society
Année:
2012
Type:
Article
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