Methotrexate for Treatment of Tubal Pregnancy / 대한산부인과학회잡지
Korean Journal of Obstetrics and Gynecology
;
: 2118-2122, 2003.
Article
Dans Coréen
| WPRIM
| ID: wpr-79250
ABSTRACT
OBJECTIVE:
The purpose of this study was to evaluate value of methotretrexate (MTX) in the treatment of tubal pregnancy.METHODS:
28 patients with unruptured tubal pregnancy were treated alternately with four doses of intramuscular MTX (1.0 mg/kg) and four doses of intramuscular citrovorum factor (0.1 mg/kg). Patients considered eligible for MTX treatment of tubal pregnancy were those with unruptured tubal pregnancyRESULTS:
26 patients (92.9%) showed normal level in serum beta-hCG and normal fingings in USG after MTX/citrovorum factor therapy. Mean age of the patients was 29.1 years (range 20-41 years). Mean gestational age was 6 weeks (range 5 weeks-8 weeks 2 days). Mean gestational sac size was 19.3 +/- 8.42 mm (range 8-33 mm). Fetal heart beat was absent in all cases on USG. Mean beta-hCG at diagnosis was 3199 +/- 2145 mIU/ml (range 235-6650 mIU/ml). Mean resolution time of beta-hCG was 32.6 +/- 14.24 days (range 12-62 days). Two patients showed increasing concentrations of beta-hCG after therapy and they underwent salpingectomy. No patient experienced severe complications such as vomiting, diarrhea, bone marrow aplasia, ulcerative stomatitis, dermatitis, pneumonitis and alopecia.CONCLUSION:
MTX is safe and effective as a primary therapy for those with unruptured tubal pregnancy
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pneumopathie infectieuse
/
Grossesse tubaire
/
Vomissement
/
Moelle osseuse
/
Méthotrexate
/
Leucovorine
/
Échographie
/
Âge gestationnel
/
Dermatite
/
Diagnostic
Type d'étude:
Etude diagnostique
Limites du sujet:
Femelle
/
Humains
/
Grossesse
langue:
Coréen
Texte intégral:
Korean Journal of Obstetrics and Gynecology
Année:
2003
Type:
Article
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Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pneumopathie infectieuse
/
Grossesse tubaire
/
Vomissement
/
Moelle osseuse
/
Méthotrexate
/
Leucovorine
/
Échographie
/
Âge gestationnel
/
Dermatite
/
Diagnostic
Type d'étude:
Etude diagnostique
Limites du sujet:
Femelle
/
Humains
/
Grossesse
langue:
Coréen
Texte intégral:
Korean Journal of Obstetrics and Gynecology
Année:
2003
Type:
Article