Intravenous thrombolytic therapy for wake-up stroke under the guidance of neuroimaging / 国际脑血管病杂志

ABSTRACT

About a quarter of acute ischemic strokes are wake-up strokes. Due to the uncertainty of the onset time, patients with wake-up stroke were considered to be unable to receive intravenous thrombolysis. Although the current guidelines recommend that the time window for intravenous thrombolytic therapy is 4.5 h, recent studies have shown that intravenous thrombolytic therapy is safe and effective for patients with wake-up stroke after neuroimaging screening. This article reviews the recent research progress on intravenous thrombolytic therapy for wake-up stroke under the guidance of neuroimaging in order to provide a reference for clinical practice.