Analysis of high risk factors and clinical characteristics of 48 cases with ischemic colonic disease / 中国基层医药

ABSTRACT

Objective@#To investigate the clinical manifestations, endoscopy, pathological features and highrisk factors of ischemic colitis(IC).@*Methods@#The clinical data of 48 inpatients with IC in the Traditional Chinese Medicine Hospital of Yuhuan from January 2016 to December 2017 were analyzed retrospectively.The risk factors of IC were analyzed by logistic regression.@*Results@#IC patients had chronic diseases such as hypertension, hyperlipidemia and diabetes.Clinical symptoms included abdominal pain and bloody stool.Colonoscopy showed that the lesions of colonic mucosa were distributed regionally, manifested as edema, hemorrhage, erosion and pleomorphic ulcer.In severe cases, stenosis of the lumen could be seen.Pathological findings included necrosis, mucosal edema, hemorrhage, ulcer formation, submucosal hemorrhage and inflammatory cell infiltration.Laboratory examination leukocyte, serum apolipoprotein B, serum fibrinogen, neutrophil, D-dimer, serum TG and TC were higher than normal levels.Logistic regression results showed that hypertension(OR=4.03, P=0.014), diabetes(OR=2.61, P=0.020), high triglyceride (OR=3.21, P=0.022), atrial fibrillation and other factors(OR=2.50, P=0.017) were closely related to the incidence of IC.@*Conclusion@#The symptoms of IC are not typical.Early diagnosis should be made by colonoscopy.Hypertension, diabetes, hyperlipidemia and atrial fibrillation are risk factors of IC.