Your browser doesn't support javascript.
loading
Endoscopic submucosal dissection of gastric subepithelial tumors: a systematic review and meta-analysis
The Korean Journal of Internal Medicine ; : 860-871, 2016.
Article Dans Anglais | WPRIM | ID: wpr-81015
ABSTRACT
BACKGROUND/

AIMS:

To evaluate the therapeutic outcomes of the endoscopic submucosal dissection (ESD) technique for the treatment of gastric subepithelial tumors (SETs).

METHODS:

A systematic literature review was conducted using the core databases. Data on the complete resection rates and the procedure-related perforation rates were extracted and analyzed. A random effects model was then applied for this meta-analysis.

RESULTS:

In all, 288 patients with 290 SETs were enrolled from nine studies (44 SETs originated from the submucosal layer; 246 SETs originated from the muscularis propria layer). The mean diameter of the lesions ranged from 17.99 to 38 mm. Overall, the pooled complete resection rate was estimated to be 86.2% (95% confidence interval [CI], 78.9 to 91.3). If the analysis was limited to the lesions that originated from the submucosal layer, the pooled complete resection rate was 91.4% (95% CI, 77.9 to 97). If the analysis was limited to the lesions that originated from the muscularis propria, the pooled complete resection rate was 84.4% (95% CI, 78.7 to 88.8). The pooled procedure-related gastric perforation rate was 13% (95% CI, 9.4 to 17.6). Sensitivity analyses showed consistent results. Finally, publication bias was not detected.

CONCLUSIONS:

ESD, including endoscopic muscularis dissection, is a technically feasible procedure for the treatment of SETs. However, selection bias is suspected from the enrolled studies. For the development of a proper indication of ESD for SETs, further studies are needed.
Sujets)

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Biais de sélection / Biais de publication / Tumeurs stromales gastro-intestinales Type d'étude: Revues systématiques évaluées Limites du sujet: Humains langue: Anglais Texte intégral: The Korean Journal of Internal Medicine Année: 2016 Type: Article

Documents relatifs à ce sujet

MEDLINE

...
LILACS

LIS

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Biais de sélection / Biais de publication / Tumeurs stromales gastro-intestinales Type d'étude: Revues systématiques évaluées Limites du sujet: Humains langue: Anglais Texte intégral: The Korean Journal of Internal Medicine Année: 2016 Type: Article