Optimization of the processing technology of Fructus Arctii by response surface methodology / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 222-231, 2015.
Article
Dans Anglais
| WPRIM
| ID: wpr-812153
ABSTRACT
The present study was designed to optimize the processing of Fructus Arctii by response surface methodology (RSM). Based on single factor studies, a three-variable, three-level Box-Behnken design (BBD) was used to monitor the effects of independent variables, including processing temperature and time, on the dependent variables. Response surfaces and contour plots of the contents of total lignans, chlorogenic acid, arctiin, and arctigenin were obtained through ultraviolet and visible (UV-Vis) monitoring and high performance liquid chromatography (HPLC). Fructus Arctii should be processed under heating in a pot at 311 °C, medicine at 119 °C for 123s with flipping frequently. The experimental values under the optimized processing technology were consistent with the predicted values. In conclusion, RSM is an effective method to optimize the processing of traditional Chinese medicine (TCM).
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Propriétés de surface
/
Médicaments issus de plantes chinoises
/
Chimie
/
Chimie pharmaceutique
/
Acide chlorogénique
/
Chromatographie en phase liquide à haute performance
/
Technologie pharmaceutique
/
Lignanes
/
Arctium
/
Furanes
Type d'étude:
Étude pronostique
langue:
Anglais
Texte intégral:
Chinese Journal of Natural Medicines (English Ed.)
Année:
2015
Type:
Article
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