Identfication of new naphthalenones from Juglans mandshurica and evalution of their anticancer activities / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 707-710, 2015.
Article
Dans Anglais
| WPRIM
| ID: wpr-812491
ABSTRACT
Two new naphthalenone compounds were isolated from green walnut husks of Juglans mandshurica and their structures were identified as 4-butoxybutoxy-5,8-dihydroxy-3,4-dihydro-2H-naphthalen-1-one (1), 4-ethoxyethoxy-5,8-dihydroxy-3,4-dihydro-2H-naphthalen-1-one (2). Compounds 1 and 2 were named as Juglanstetralone A (1) and Juglanstetralone B (2). Compound 1 showed more significant anti-tumor activity than 2 against gastric cancer BGC-823 cells, wih the IC50 of 125.89 (g(mL(-1).
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pharmacologie
/
Tumeurs de l'estomac
/
Extraits de plantes
/
Carcinomes
/
Chimie
/
Juglans
/
Lignée cellulaire tumorale
/
Utilisations thérapeutiques
/
Traitement médicamenteux
/
Phytothérapie
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Chinese Journal of Natural Medicines (English Ed.)
Année:
2015
Type:
Article
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