Biotoxicology and biodynamics of silica nanoparticle / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 6-8, 2006.
Article
Dans Chinois
| WPRIM
| ID: wpr-813778
ABSTRACT
OBJECTIVE@#To investigate the toxicology and biodynamics of silica nanoparticle.@*METHODS@#The silica nanoparticles were injected into mice through tail vein, and the mice were amphimixised, the urine was collected in different time, variations of pathology in organs and tissues of the mice were detected. At the same time, the silica nanoparticles' distribution in the tissues was observed through electron microscope.@*RESULTS@#The silica nanoparticles were detected in all tissues and urine of the mice. The injected mice can reproduce as normal.@*CONCLUSION@#The silica nanoparticles do not have toxicity and can be used in vivo.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Test de matériaux
/
Pharmacocinétique
/
Distribution tissulaire
/
Transfection
/
Silice
/
Nanostructures
/
Toxicité
Limites du sujet:
Animaux
langue:
Chinois
Texte intégral:
Journal of Central South University(Medical Sciences)
Année:
2006
Type:
Article
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