Clinicopathologic features and diagnosis of 18 patients with angioimmunoblastic T-cell lymphoma / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 523-526, 2009.
Article
Dans Chinois
| WPRIM
| ID: wpr-814293
ABSTRACT
OBJECTIVE@#To explore the clinical and pathologic features of angioimmunoblastic T-cell lymphoma(AITL) and provide evidence for diagnosis.@*METHODS@#Eighteen AITL patients (9 males and 9 females aged from 14 to 70 years) were retrospectively analyzed in Xiangya Hospital of Central South University from July 2002 to September 2007.@*RESULTS@#Characteristic features at the presentation of AITL included generalized lymphadenopathy, fever, splenomegaly, and skin rashes with polyclonal hyper-gammaglobulinemia and other hematological abnormalities (such as Coombs-positive hemolytic anemia), which often involved the bone marrow and had well-described histologic features. The positive rate for CXCL13 was 93.3%.@*CONCLUSION@#Repeated lymphadenbiopsy is helpful for AITL diagnosis. Routine histological and immunohistochemical examinations (especially including CXCL13) play significant role in the diagnosis and differential diagnosis of AITL.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Anatomopathologie
/
Études rétrospectives
/
Lymphome T périphérique
/
Diagnostic
/
Chimiokine CXCL13
/
Lymphadénopathie angio-immunoblastique
/
Métabolisme
Type d'étude:
Etude diagnostique
/
Étude observationnelle
Limites du sujet:
Adolescent
/
Adulte
/
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
Journal of Central South University(Medical Sciences)
Année:
2009
Type:
Article
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