Serum vitamin D levels in postmenopausal women with type 2 diabetes mellitus / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
; (12): 1051-1056, 2013.
Article
de Zh
| WPRIM
| ID: wpr-814821
Bibliothèque responsable:
WPRO
ABSTRACT
OBJECTIVE@#To investigate the correlation between serum vitamin D levels and index of glucose and lipid metabolism in postmenopausal women with type 2 diabetes mellitus (T2DM).@*METHODS@#A total of 44 postmenopausal women with T2DM and 41 healthy postmenopausal women were matched with age, body mass index and menopausal duration. The serum vitamin D was detected by enzyme-linked immuno-sorbent assay (ELISA).@*RESULTS@#Compared with the control group, the level of 25(OH)D3 in postmenopausal women with T2DM was lower, with no statistical significance. Multiple regression analysis revealed that only BMI(bj'=-0.372, P<0.05) was independently related to 25(OH)D3 with statistical significance. The percentages of 25(OH)D3 deficiency in all subjects in the control group and in the T2DM group were 84.7%, 80.5%, and 88.6%, respectively. The 25(OH)D3 deficiency in the T2DM group was more prevalent than that in the control group, with no statistical difference (P=0.372). The binary logistic regression analysis showed the serum 25(OH)D3 level was not related to the risk of diabetes.@*CONCLUSION@#Compared with the control group, a lower 25(OH)D3 level and a higher rate of 25(OH)D3 deficiency is found in T2DM subjects. When rectified by BMI, these is no significant difference. In postmenopausal women, hypovitaminosis D is associated with obesity and dyslipidemia, but not with the risk of T2DM.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Carence en vitamine D
/
Sang
/
Calcitriol
/
Indice de masse corporelle
/
Études cas-témoins
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Prévalence
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Post-ménopause
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Diabète de type 2
Type d'étude:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limites du sujet:
Female
/
Humans
langue:
Zh
Texte intégral:
Journal of Central South University(Medical Sciences)
Année:
2013
Type:
Article