Progress in studies on the role of β-catenin in regulating the self-renewal and pluripotency of embryonic stem cells / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 206-211, 2016.
Article
Dans Chinois
| WPRIM
| ID: wpr-815052
ABSTRACT
Embryonic stem cells (ESCs) is one of the best cell types for regenerative medicine. It is derived from inner cell mass of the blastocyst stage and characterized by self-renewal and pluripotency, which are regulated by kinds of signal molecules, such as the Wnt/β-catenin signaling pathway. β-catenin is a multifunctional protein and plays a key role in Wnt/β-catenin signaling pathway. β-catenin involves self-renewal of ESCs and promotes the differentiation of ESCs into three primary germ layers in space and time. Elucidating the mechanisms of β-catenin in regulating the self-renewal and pluripotency of ESCs will pave the way to use it in research and application.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Physiologie
/
Blastocyste
/
Différenciation cellulaire
/
Biologie cellulaire
/
Bêta-Caténine
/
Cellules souches embryonnaires
/
Voie de signalisation Wnt
Limites du sujet:
Humains
langue:
Chinois
Texte intégral:
Journal of Central South University(Medical Sciences)
Année:
2016
Type:
Article
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