Brain structure analysis for patients with antisocial personality disorder by MRI / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 123-128, 2015.
Article
Dans Chinois
| WPRIM
| ID: wpr-815201
ABSTRACT
OBJECTIVE@#To investigate the structural abnormalities of brain in patients with antisocial personality disorder (ASPD) but without alcoholism and drug abuse.@*METHODS@#Volunteers from Hunan Reformatory (n=36) and the matched healthy subjects (n=26) were examined by high-spatial resolution magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI). Voxel-based morphometry and fractional anisotropy (FA) maps were generated for each subject to reveal structural abnormalities in patients with ASPD.@*RESULTS@#Compared with the healthy controls, ASPD patients showed significantly higher gray matter volumes in the inferior parietal lobule (P≤0.001, uncorrected), white matter volumes in the precuneus (P≤0.001, uncorrected), FA in the left lingual gyrus, bilateral precuneus, right superior frontal gyrus and right middle temporal gyrus (P≤0.01, uncorrected).@*CONCLUSION@#Our results revealed the abnormal neuroanatomical features in ASPD patients, which might be related to the external behavioral traits in ASPD patients.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Encéphale
/
Imagerie par résonance magnétique
/
Études cas-témoins
/
Anisotropie
/
Diagnostic
/
Imagerie par tenseur de diffusion
/
Trouble de la personnalité de type antisocial
Type d'étude:
Etude diagnostique
/
Étude observationnelle
Limites du sujet:
Humains
langue:
Chinois
Texte intégral:
Journal of Central South University(Medical Sciences)
Année:
2015
Type:
Article
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