Carotid intima-media thickness and estimated glomerular filtration rate in hypertensive patients / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 465-470, 2014.
Article
Dans Chinois
| WPRIM
| ID: wpr-815409
ABSTRACT
OBJECTIVE@#To determine the association between carotid atherosclerosis and renal function in hypertensive patients.@*METHODS@#A total of 2 809 hypertensive patients aged (56.59±10.79) years were enrolled. Carotid intima-media thickness (cIMT) was derived via B-mode ultrasonography and chronic kidney disease (CKD) was evaluated by the estimated glomerular filtration rate (eGFR) with Cockcroft- Gault method. The patients were divided into 3 groups a normal group, a thick group, and a plaque group according to the results of carotid ultrasonography.@*RESULTS@#The eGFR of the normal group was (111.09±25.61) mL/(min.1.73m(2)), that of the thick group and the plaque group was (94.45±27.14) mL/(min.1.73m(2)) and (85.98±26.92) mL/ (min.1.73m(2)). Binary logistic analysis showed that age (OR=3.590), smoking status (OR=1.543), systolic blood pressure (OR=1.018), diastolic blood pressure (OR=0.977), fasting plasma glucose (OR=1.132), triglyceride (OR=0.873) and eGFR (OR=0.986) were significantly correlated with cIMT. Subgroup analyses on different genders showed that eGFR was a significant independent risk factor in men (OR=0.991) but not in women.@*CONCLUSION@#The thicker the cIMT, the lower the eGFR in hypertensive patients. With the development of cIMT, eGFR gradually decreases and contributes to the occurrence and development of early-stage atherosclerosis in hypertensive patients.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Anatomopathologie
/
Pression sanguine
/
Imagerie diagnostique
/
Artères carotides
/
Artériopathies carotidiennes
/
Fumer
/
Facteurs de risque
/
Insuffisance rénale chronique
/
Athérosclérose
/
Épaisseur intima-média carotidienne
Type d'étude:
Etude diagnostique
/
Etude d'étiologie
/
Facteurs de risque
Limites du sujet:
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
Journal of Central South University(Medical Sciences)
Année:
2014
Type:
Article
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