Current status and perspectives of autoimmune hepatitis / 临床肝胆病杂志

ABSTRACT

Autoimmune hepatitis (AIH) is an autoimmune liver disease induced by environmental factors in individuals with genetic susceptibility, with the main features of positive serum autoantibody, hypergammaglobulinemia, elevated transaminases, and interface hepatitis. The pathogenesis of AIH remains unknown, high heterogeneity is observed in clinical diagnosis and treatment, and thus it is of great importance to establish individualized precise diagnosis and treatment. Therefore, this article reviews the research advances and difficult issues in this field.