Study on serum cytokine levels in posttraumatic stress disorder patients
Asian Pacific Journal of Tropical Medicine
;
(12): 323-325, 2012.
Article
Dans Anglais
| WPRIM
| ID: wpr-819777
ABSTRACT
OBJECTIVE@#To evaluate serum IL-2, IL-4, IL-6, IL-8, IL-10 and TNF-α levels in posttraumatic stress disorder (PTSD) patients.@*METHODS@#We utilized ELISA technology to examine cytokines such as IL-2, IL-4, IL-6, IL-8, IL-10 and TNF-α in serum from 50 well-characterized individuals with a primary DSM-IV PTSD diagnosis, and 50 age- and gender-matched healthy controls. We conservatively employed a Mann-Whitney U testing.@*RESULTS@#Individuals with primary PTSD had significantly elevated peripheral cytokine levels for all 6 different cytokines compared to age- and gender-matched healthy controls (all P<0.01).@*CONCLUSIONS@#These findings suggest that a generalized inflammatory state may be present in individuals with PTSD.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Troubles de stress post-traumatique
/
Sang
/
Test ELISA
/
Études cas-témoins
/
Interleukines
/
Facteur de nécrose tumorale alpha
/
Métabolisme
Type d'étude:
Étude observationnelle
Limites du sujet:
Adulte
/
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Asian Pacific Journal of Tropical Medicine
Année:
2012
Type:
Article
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