Risk factors for the development and progression of nonalcoholic fatty liver disease / 临床肝胆病杂志

ABSTRACT

The prevalence rate of nonalcoholic fatty liver disease (NAFLD) is increasing year by year, and at present, it has become one of the most common chronic liver diseases in adults in China. NAFLD can progress from nonalcoholic fatty degeneration of the liver to nonalcoholic steatohepatitis, liver cirrhosis, hepatocellular carcinoma, NAFLD-associated cardiovascular events, and death. This article reviews the risk factors for the development of NAFLD and the progression of NAFLD to major diseases such as liver fibrosis, liver cirrhosis, liver cancer, related cardiovascular events, and death, in order to further explore the mechanism of the development and progression of NAFLD, reduce the prevalence rate of NAFLD, slow down the progression of NAFLD, reduce the mortality rate of related diseases, and achieve better prevention and treatment.