Application value of red cell distribution width in prognosis evaluation of patients with acute myocardi‐al infarction／ / 心血管康复医学杂志

ABSTRACT

To study application value of red cell distribution width (RDW) in prognosis evaluation of pa‐tients with acute myocardial infarction (AMI).Methods: A total of 300 AMI patients of our hospital were selected as AMI group ,another 300 subjects with normal physical examination outcome simultaneously were enrolled as healthy control group.Levels of peripheral cardiac troponin I (cTnI ) ,hsCRP ,homocysteine (Hcy) and RDW in healthy control group and AMI group before and one year after treatment ,and cardiac function indexes in AMI group before and after treatment were observed .Results: Compared with healthy control group before treatment ,there were significant rise in levels of ser‐um cTnI [(0.24 ± 0.03) ng／ml vs.(19.98 ± 2.54) ng／ml] , hsCRP [(1.05 ± 0.18) mg／L vs.(17.85 ± 1.93) mg／L] , Hcy [ (6.75 ± 0.71) μmol／L vs.(29.89 ± 3.27) μmol／L] and RDW [ (10.38 ± 1.07)% vs.(17.95 ± 1.93)%] in AMI group , P＝0.001 all.On one year after treatment ,there were 57 patients (19%) with poor prognosis in AMI group . Compared with good prognosis patients before and one year after treatment ,there were significant rise in levels of cTnI , hsCRP ,Hcy ,RDW ,left ventricular end‐systolic volume index (LVESVI) and left ventricular end‐diastolic volume index (LVEDVI) ,and significant reduction in LVEF in poor prognosis patients ,P＜0.05 or ＜0.01 ;Pearson correlation analy‐sis indicated that RDW was significant positively correlated with cTnI ,hsCRP ,Hcy ,LVESVI and LVEDVI ( r＝0. 420－ 0.498 , P＝0.001 all) ,and significant inversely correlated with LVEF ( r＝ －0.468 , P＝0. 001).Conclusion:RDW is correlated with myocardial injury markers ,inflammatory factors and cardiac function ,which contribute to evalu‐ate the prognosis of AMI patients .