A new antiviral isoquinoline alkaloid from Thalictrum glandulosissimum / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 2568-2570, 2020.
Article
de Zh
| WPRIM
| ID: wpr-828044
Bibliothèque responsable:
WPRO
ABSTRACT
A new isoquinoline alkaloid(1) has been isolated from the whole plant of Thalictrum glandulosissimum by using various chromatographic techniques, including silica gel, sephadex, MCI-gel resin, and RP-HPLC, and its structure was determined as 1-(6-hydroxy-7-methylisoquinolin-1-yl) ethantone by physicochemical properties and spectroscopic data. This compound was evaluated for anti-tobacco mosaic virus(TMV) activity. The results showed that it had prominent anti-TMV activity with inhibition rates of 28.4%. This rate was closed to that of positive control.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Antiviraux
/
Virus de la mosaïque du tabac
/
Thalictrum
/
Alcaloïdes
/
Isoquinoléines
langue:
Zh
Texte intégral:
China Journal of Chinese Materia Medica
Année:
2020
Type:
Article