Your browser doesn't support javascript.
loading
Effect of breastfeeding on insulin sensitivity in infants with intrauterine growth retardation: a follow-up study / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics ; (12): 701-705, 2020.
Article Dans Chinois | WPRIM | ID: wpr-828681
ABSTRACT
OBJECTIVE@#To study insulin sensitivity and the serum level of adiponectin in infants with intrauterine growth retardation (IUGR) and the effect of breastfeeding on the insulin sensitivity through a follow-up study.@*METHODS@#A total of 106 full-term IUGR infants who were hospitalized from October 2014 to October 2018 were enrolled as the IUGR group, and 90 full-term appropriate for gestational age (AGA) infants who were born during the same period of time were enrolled as the AGA group. Birth weight and body length were recorded. Serum levels of fasting blood glucose (FBG), triglyceride (TG), low-density lipoprotein (LDL), high-density lipoprotein (HDL), insulin, and adiponectin were measured on day 7 after birth. Homeostasis model assessment of insulin resistance (HOMA-IR) was calculated. According to the feeding pattern, the IUGR group was further divided into a breastfeeding group with 37 infants and a formula feeding group with 42 infants. The above serum indices and growth indices were also measured at the age of 3 and 6 months.@*RESULTS@#Compared with the AGA group, the IUGR group had significantly increased levels in serum insulin and HOMA-IR and a significantly decreased level of adiponectin (P0.05). In the breastfeeding group, serum insulin and HOMA-IR decreased and adiponectin level increased over the time of breastfeeding (P<0.05).@*CONCLUSIONS@#Insulin sensitivity decreases in the early stage after birth in IUGR infants, and breastfeeding can improve insulin sensitivity.
Sujets)
Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Insulinorésistance / Études de suivi / Adiponectine / Retard de croissance intra-utérin / Insuline Type d'étude: Etude diagnostique / Étude observationnelle / Étude pronostique Limites du sujet: Humains / Bébé / Nouveau-né langue: Chinois Texte intégral: Chinese Journal of Contemporary Pediatrics Année: 2020 Type: Article

Documents relatifs à ce sujet

MEDLINE

...
LILACS

LIS

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Insulinorésistance / Études de suivi / Adiponectine / Retard de croissance intra-utérin / Insuline Type d'étude: Etude diagnostique / Étude observationnelle / Étude pronostique Limites du sujet: Humains / Bébé / Nouveau-né langue: Chinois Texte intégral: Chinese Journal of Contemporary Pediatrics Année: 2020 Type: Article