Risk or Beneficial Factors Associated with Unplanned Revascularization Risk Following Percutaneous Coronary Intervention: A Large Single-Center Data / 生物医学与环境科学（英文）

ABSTRACT

Objective@#To analyze factors associated with unplanned revascularization (UR) risk in patients with coronary artery disease (CAD) who underwent percutaneous coronary intervention (PCI).@*Methods@#A total of 10,640 cases with CAD who underwent PCI were analyzed. Multivariate COX regressions and competing risk regressions were applied.@*Results@#The patients who underwent UR following PCI in 30 days, 1, and 2 years accounted for 0.3%, 6.5%, and 8.7%, respectively. After multivariate adjustment, the number of target lesions [hazard ratio ( ) = 2.320; 95% confidence interval ( ) 1.643-3.277; < 0.001], time of procedure ( = 1.006; 95% 1.001-1.010; = 0.014), body mass index ( = 1.104; 95% 1.006-1.210; = 0.036), incomplete revascularization (ICR) ( = 2.476; 95% 1.030-5.952; = 0.043), and age ( 1.037; 95% 1.000-1.075; = 0.048) were determined as independent risk factors of 30-day UR. Factors, including low-molecular-weight heparin or fondaparinux ( = 0.618; 95% 0.531-0.719; < 0.001), second-generation durable polymer drug-eluting stent ( 0.713; 95% 0.624-0.814; < 0.001), left anterior descending artery involvement ( = 0.654; 95% 0.530-0.807; < 0.001), and age ( = 0.992; 95% 0.985-0.998; = 0.014), were independently associated with decreased two-year UR risk. While, Synergy Between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery score ( = 1.024; 95% 1.014-1.033; < 0.001) and ICR ( = 1.549; 95% 1.290-1.860; < 0.001) were negatively associated with two-year UR risk.@*Conclusion@#Specific factors were positively or negatively associated with short- and medium-long-term UR following PCI.