Your browser doesn't support javascript.
loading
Hypoxia inducible factor in postmenopausal osteoporosis: Recent progress / 第二军医大学学报
Article de Zh | WPRIM | ID: wpr-838393
Bibliothèque responsable: WPRO
ABSTRACT
Hypoxia inducible factor (HIF) plays a key role in the cellular response to hypoxia, and is involved in a variety of pathological and physiological processes such as glucose metabolism, vascular remodeling and erythropoiesis. Growing research suggests that HIF has an important effect on osteogenesis, bone resorption and angiogenesis; while the deterioration of bone vascular structures and functions is closely related to the development and progression of postmenopausal osteoporosis. In this review, we summarized the relationship between HIF and postmenopausal osteoporosis based on the roles of HIF in osteogenesis, bone resorption and angiogenesis, hoping to evaluate its therapeutic prospect on postmenopausal osteoporosis.
Mots clés
Texte intégral: 1 Indice: WPRIM langue: Zh Texte intégral: Academic Journal of Second Military Medical University Année: 2017 Type: Article
Texte intégral: 1 Indice: WPRIM langue: Zh Texte intégral: Academic Journal of Second Military Medical University Année: 2017 Type: Article