Effects of target-controlled infusion of propofol or sevoflurane combined with remifentanil on cerebral oxygen metabolism: A comparison study / 第二军医大学学报
Academic Journal of Second Military Medical University
;
(12): 804-807, 2014.
Article
Dans Chinois
| WPRIM
| ID: wpr-839191
ABSTRACT
Objective:
To compare the effects of target-controlled infusion (TCI) between propofol/remifentanil and sevoflurane/remifentanil during anesthesia on cerebral oxygen metabolism in patients undergoing brain tumor surgery, so as to provide references for clinical practice.Methods:
A double-blind randomized, controlled trial was conducted with sixty participants, which were equally assigned to two groups. Patients in the PR Group were induced by TCI of propofol/remifentanil combination and those in the SR Group were anesthetized with sevoflurane/remifentanil combination. Blood samples were collected at different time points to measure jugular bulb venous oxygen saturation (SjvO2) and generate arteriovenous oxygen content difference (Da-jvO2). The hemodynamic parameters and duration of surgery or anesthesia of each participant were also monitored and recorded.Results:
No significant difference was found regarding to the hemodynamic parameters or duration of surgery/anesthesia between the two groups. SjvO2 was found significantly higher and Da-jvO2 was significantly lower in the SR group than those in the PR group(P<0.01).Conclusion:
Combined anesthesia with propofol/remifentanil vs sevoflurane/remifentanil are both safe for patients undergoing cerebral tumor operation; and sevoflurane/remifentanil seems to provide better oxygen supply and has more rapid post-operation recovery; however, sevoflurane/remifentanil can improve cerebral oxygenation.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Type d'étude:
Essai clinique contrôlé
langue:
Chinois
Texte intégral:
Academic Journal of Second Military Medical University
Année:
2014
Type:
Article
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