Analysis of depression and endothelial function in patients with chronic ischemia heart failure / 第二军医大学学报
Academic Journal of Second Military Medical University
;
(12): 1319-1322, 2010.
Article
Dans Chinois
| WPRIM
| ID: wpr-840155
ABSTRACT
Objective:
To investigate the endothelial function of chronic ischemia heart failure (CIHF) patients complicated with depression.Methods:
The depression statuses were evaluated by Self-rating Depression Scale (SDS) in 56 patients with documented stable chronic ischemia heart failure. The patients were assigned to depression group (n = 20) or non-depression group(n = 36) based on their standard SDS scores. The flow-mediated dilation(FMD) of the brachial artery was assessed by ultrasound in the two groups, and the plasma ET-1 and NO levels were determined so as to evaluate the endothelial function.Results:
The incidence of depression was 35.7% in the 56 patients. Patients in the depression group showed significantly lower FMD compared with the non-depression group([5.97±0.78]% vs [6.66±0.83]% , P<0.05). Plasma NO level ([48.90±9.82] μmol/L vs [55.13±10.32] μmol/L, P<0.05) was lower and ET-1 level ([83.35±13.39] ng/L vs [74.67±10.95] ng/L, P<0.05) was higher in the depression group than in the non-depression group.Conclusion:
CIHF patients with depression have a more severe damage of endothelial function than those without depression.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Academic Journal of Second Military Medical University
Année:
2010
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS