Bone morphogenetic protein-oriented multi-factor combined application in promoting osteogenesis: Recent progress / 第二军医大学学报

ABSTRACT

Bone morphogenetic proteins (BMPs) play a pivotal role in the formation, induction and repair of the bone; BMPs have been confirmed to induce bone formation. Transforming growth factor-beta, insulin-like growth factor-I and basic fibroblast growth factor also contribute to bone formation; combination of the factors with BMPs can promote the healing of fracture and non-union, which may have a bright future in orthopedics.