Differences of activated brain areas during brain error-monitoring in schizophrenia patients / 第二军医大学学报
Academic Journal of Second Military Medical University
;
(12): 48-52, 2010.
Article
Dans Chinois
| WPRIM
| ID: wpr-840676
ABSTRACT
Objective:
To study the differences of activated brain areas during brain error monitoring in schizophrenia patients.Methods:
The latencies and amplitudes of error related negativity (ERN) were obtained in 16 patients with first episode schizophrenia and 25 normal controls by high-density event related potential (ERP) technique, and the activated areas were analyzed by low resolution electromagnetic tomography (LORETA).Results:
The correct response rate was significantly lower in the schizophrenia participant group than in the control group (P<0.01), and the reaction periods of correct responses and incorrect responses were significantly longer in the schizophrenia group than in the control group (P<0.05, P<0.01). The ERN latencies in the schizophrenic patients were significantly longer on Cz and Pz electrodes compared with those in the control subjects (P<0.05) and ERN amplitudes were significantly smaller than those in the controls (P<0.05). The activation of insula, superior temporal gyrus, middle temporal gyrus, and inferior parietal lobule were obviously lower in the schizophrenic participants than in the controls.Conclusion:
Some brain area, such as insular, may contribute to the dysfunction of error monitoring in schizophrenia patients.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Type d'étude:
Étude pronostique
langue:
Chinois
Texte intégral:
Academic Journal of Second Military Medical University
Année:
2010
Type:
Article
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